The company’s fluorescent probes (probes, v5) include hundreds of clinical diagnostic probes, scientific research probes and companion diagnostics of precise cancer treatment as described later. We have various types of products, especially companion diagnostics. Among these products are designed and made by ourselves. Fluorescent probes can be either sold independently or included in fluorescent inspection kit.
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1.FISH Fluorescent Probe (v5)
2.FISH Fluorescent Probe (v5) + Hybridization Reagent (v3-a or v3-b or v3-c)
3.FISH Specimen Processing Kit (v0-a1+v0-a3+v0-b2) and (v0-a2+v0-a3+v0-b2)
4.FISH Fluorescent Inspection Rapid Kit (v1-a1+v2+v3a+v4)
5.FISH Fluorescent Inspection Safety Kit (v1-a1+v2+v3b+v4)
6.FISH Fluorescence Detection High-resolution Kit (v1-a2+v2+v3c+v4)
7.Sample Processing + FISH Fluorescence Test Set (v0+v1+v2+v3-a+v4+v5)
8.Probe
Breast Cancer
Gene: HER2、CEP17、HER3、CEP12、HER4、CEP2、TOPO2A、NF1、BRCA1、P53。
Lung Cancer
Gene: ALK(Fusion assay)、EML4(Fusion assay)、ALK(Break-apart assay)(Fusion assay)、EML4(Break-apart assay)(Fusion assay)、ROS1(Break-apart assay)、RET 5’、RET 3’。
Renal Cell Carcinoma / Alveolar Soft Part Sarcoma
Gene: 3’-TFE3 Centromeric、3’-TFE3 Centromeric、5’-TFE3 Telomeric、5’-TFE3 Telomeric。
EWSR1 rearrangement
Gene: EWSR1-5'、EWSR1-3'、EWSR1-3'。
Desmoplastic small round cell tumor
Gene: EWSR1、WT1(green)、WT1(green)。
Prostate Cancer
Gene: TMPRSS2 5'、ERG 5’、ERG 3’、PTEN、CEP10。
Colorectal Cancer / Lung Cancer
Gene: EGFR(red)、CEP 7、CEP 7、c-MET(red)。
Hepatoma
Gene: CLIC1、CEP 60。
Lymphoma
Gene:FGFR1、PDGFRA、PDGFRB。
Dermatofibrosarcoma protuberans
Gene: COL1A1、platelet-derived growth factor B chain (PDGFB)。
Fip1-like 1 (FIP1L1) gene
Gene: FIP1L1。
Pre-natal
Gene: RB1(red)、ERG 5’(green)。
Homo sapiens ligand of numb-protein X 1 (LNX1)
Gene: LNX1。
Homo sapiens cysteine-rich hydrophobic domain 2 (CHIC2)
Gene: CHIC2。
(Congenital fibrosarcoma / mesoblastic nephroma) ETV6-NTRK3
Gene: ETV6(red) Telomeric to ETV6、ETV6(green) Centromeric to ETV6、NTRK3(red) Telomeric to NTRK3、NTRK3(green) Centromeric to NTRK3。
Synovial Sarcoma
Gene: SS18 3’、 SS18 3’、 SS18 3’、 SS18 5’、 SS18 5’、 SS18 5’。
FUS rearrangement (Break-apart)
Gene: FUS-5’(red)、FUS-5’(red)、FUS-3’(green)、FUS-3’(green)。
MYEOV-IGH t(11;14) dual color, dual-fusion assay
Gene: Homo sapiens myeloma overexpressed (MYEOV) 5’、(MYEOV) 3’、IGH 5’、IGH 3’。
Myeloperoxidase(MPO)
Gene: MPO。
BCR/ABL dual color, dual-fusion probe
Gene: BCRBCR(Breakpoint cluster region)。
Tuberous Sclerosis
Gene: TSC-1、TSC-2、CEP16、CEP16、CEP16、CEP16(q12.1)。
NPC/ EBV-related gastric cancer
Gene: UBR5-5’、ZNF423-5’、ZNF423-3’、CEP18(aqua)。
hTERC(3q26) / 3q11
Gene: hTERC、3q11。
AML(RUNX1)/ETO(RUNX1T) t(8;21) Dual-color Fusion
Gene: AML(RUNX1)、ETO(RUNX1T)。
PML/RARA t(15,17) Fusion
Gene: PML、RARA。
TEL/AML t(12,21) Fusion
Gene: TEL、AML。
MYC/IGH t(8;14) Fusion
Gene: MYC、IGH。
BCL1/IGH t(11;14) Fusion
Gene: BCL1。
BCL2/IGH t(14;18) Fusion
Gene: BCL2。
MALT (18q21) Break
Gene: MALT。
BCL6 (3q27)
Gene: BCL6-5'、BCL6-3'。
p16(9q21)/ 9q21
Gene: p16。
MYCN (2p24) /LAF (2q21)
Gene: MYCN、LAF。
1p/19q deletion
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